Michael, instead of Carriage Return / Line Feed are you referring to CSRF, or Cross-site Request Forgery? The Secure Forms feature of ExpressionEngine will provide you with CSRF protection. As Ingmar stated, carriage returns and line feeds will not impact PHP/MySQL (with rare exception, not affecting ExpressionEngine).
Edit-add: Specifically, CRLF will not affect a query to MySQL, and the email headers for the contact form are written specifically by EE, not passing user input off directly to these. Even if you use an open form with a To: field, its input is validated, split into email address, and assembled by ExpressionEngine apart from how the user keyed it in.