Currently I am using e-Text Editor (which now has built in FTP and can handle most TextMate bundles and plays nice with SVN. All shortcuts are editable and syntax highlighting is limited by imagination. Code completion is tied to the TM bundles and they have had some odd changes lately but nonetheless I find it fast and lean.
Immediately prior (and still have installed) use HTML-Kit since it has excellent ftp for live edits.
I am mostly a designer but I wouldn’t move back to using Dreamweaver because I don’t need to eat 250 MB ram for a text-editor. Once I learned that I could actually develop faster in code view I ditched it for Notepad++ then HTML-Kit and now e.
I’ve also used Eclipse with PDT on some personal PHP projects but I find it clunky but the QuantumDb Plugin is kick a$$ and way faster than using phpMyAdmin.
I would never -ever use the synching files in DW again since its FTP is clearly pushing golfballs through garden hoses. I edit locally and push changed files manually. In addition, having DW + Fireworks + Illustrator + Photoshop == 0 Productivity as it crippled my (at the time) machine. I guess Adobe felt that people had 1GB of RAM (back then) they may as well use it all. Illustrator has tonnes of unresolved Bugs. Bye Bye Creative Suite. The only adobe app I regularly use is Fireworks since it hasn’t been butchered by Adobe’s bloatware team.
I’ll definately look at Aptana for PHPdev.